TY - JOUR AU - Nath, Dr Gopal Chandra PY - 2019/05/27 Y2 - 2024/03/29 TI - Study on Lipid profile in hypothyroidism. JF - Jour Med Resh and Health Sci JA - jmrhs VL - 2 IS - 5 SE - ORIGINAL ARTICLES DO - 10.15520/jmrhs.v2i5.63 UR - http://jmrhs.info/index.php/jmrhs/article/view/63 SP - 621-623 AB - <p><strong>Background:</strong> <strong>Dyslipidemia is one of the common disorders seen in most of the hypothyroid patients. Objective: To study the lipid profile in patients with hypothyroidism.&nbsp;&nbsp; Methods: The study was carried out in our hospital for a period of one year. The study included 100 hypothyroid &nbsp;patients and 100 healthy&nbsp; subjects .Their serum samples were assessed for TSH,T4 and T3 , total cholesterol , triglycerides, low density lipoprotein(LDL) cholesterol&nbsp; and high density lipoprotein(HDL) cholesterol&nbsp; by using standard biochemical methods after taking informed consent. Results: Out of 100 hypothyroid patients 45 (45%) were males and 55 (55%) were females. 75 patients presented with clinical hypothyroidism and 25 patients with subclinical hypothyroidism. Maximum number of patients were in age group of 30-45 years. 85.3% of clinical hypothyroid patients showed high serum cholesterol level, while 44% of subclinical hypothyroid patients showed high serum cholesterol level.</strong> <strong>68% of subclinical hypothyroid patients showed high serum triglyceride level (&gt;150mg/dl), while 85.3% of clinical hypothyroidism patients showed high triglyceride level.</strong></p><p><strong>Serum LDL level was high (&gt;160 mg/dl) in 78.6% of patients with clinical hypothyroidism, while&nbsp; 68% of patients with subclinical hypothyroidism showed higher value. </strong><strong>40% of subclinical hypothyroid patients showed low(&lt;40 mg/dl) serum HDL value while all patients with clinical hypothyroidism had low serum HDL level.</strong> <strong>Conclusion: The frequencies of the high cholesterol, high TG , high LDL with low HDL levels were higher in the hypothyroid group, thus indicating that hypothyroid patients were more prone for dyslipidemia, which&nbsp; is a major risk factor for cardiovascular disorders.&nbsp;&nbsp;</strong></p> ER -