Journal of Medical Research and Health Sciences http://jmrhs.info/index.php/jmrhs <p><strong>Journal of Medical Research and Health Sciences</strong>&nbsp; aims to improve health status and quality of care for individuals, families and communities. The Health Science Journal (Print ISSN : 2589-9023, Online ISSN: 2589-9031) aspires to provide the scientific knowledge through the publication of peer-reviewed, high quality, scientific papers and other material on all topics related to Biochemistry, Biotechnology, Health engineering, Epidemiology, Genetics, Nursing, Pharmacology, Pharmacy, Public health, Psychology, Physical therapy, and Medicine ensuring a rapid turn-around time possible for reviewing and publishing of articles freely for research, teaching and reference purposes.</p> en-US Mon, 01 Jul 2019 00:00:00 +0000 OJS 3.1.1.4 http://blogs.law.harvard.edu/tech/rss 60 Placebo controlled research on herbs for prevention of coronary artery disease http://jmrhs.info/index.php/jmrhs/article/view/68 <p>Introduction: Dyslipidemia refers to a disruption of lipid metabolism with exceeding serum levels of cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C), and/or lower level of high-density lipoprotein-cholesterol (HDL-C). Serum levels of lipids and lipoprotein lipids are among the most potent and best substantiated risk factors for atherosclerotic diseases, particularly coronary heart disease.</p> <p>Design and Place of conduction: The research work was single blind placebo-controlled, conducted at Jinnah Hospital, Lahore. Research time: It was conducted from April 2017 to October 2017. Number of patients and their Age: Seventy five already diagnosed primary and secondary&nbsp; hyperlipidemic patients were selected with age range from 17 to 65 years.</p> <p>Exclusion criteria:&nbsp; Diabetes mellitus, cigarette smoking/alcohol addictive patients, peptic ulcer disease, hypothyroidism, kidney dysfunction, any heart disease and liver disease. All patients were divided in three groups (group-I, group-II, group-III), 25 in each group. Proforma for patients: Their baseline lipid profile data were taken and filed in specifically designed Performa, at start of taking medicine. Patients group division: Twenty five patients of group-I were advised to take 10 grams of Flaxseeds in three divided doses after meal. Twenty five patients of group-II were advised to take Ajwain seeds 10 grams in three divided doses after each meal for two months. Twenty five patients of group-III were provided placebo capsules, (containing grinded rice), taking one capsule after each meal. All participants were advised to take these medicines for eight weeks. Followup period: All participants were called fortnightly for their query and&nbsp; follow up. Their LDL-cholesterol, and HDL-cholesterol was determined at the hospital laboratory. Results: In two months therapy by Flaxseeds decreased LDL-cholesterol from 195.11±2.11 mg/dl &nbsp;to 190.22±3.11 mg/dl, which is significant statistically. HDL was increased from 34.53±1.65 mg/dl to 38.97±2.29 mg/d, which is also significant change. In two months therapy by AJWAIN, LDL-c reduced from 201.51±2.62 mg/dl to 197.11±2.66 mg/dl, which is significant statistically. HDL-cholesterol increased by Ajwain from 36.97±3.32 mg/dl&nbsp; to 37.45±1.87 mg/dl, which is insignificant statistically. Conclusion: It was concluded from this study that Ajwain and Flaxseeds reduces LDL-cholesterol moderately. Flaxseeds have more effect on HDL-c but Ajwain has lowest effect on this parameter. Key words: Lipids, Phytochemicals, CAD, Prevention, treatment</p> DR. SHAH MURAD, DR. M ASHRAF MEMON, DR. SEEMA, ABDUL GHAFFAR, DR. ADNAN SHAFIQUE, DR. G MUJTABA ABBASI ##submission.copyrightStatement## http://jmrhs.info/index.php/jmrhs/article/view/68 Fri, 12 Jul 2019 07:53:35 +0000 Change in Population of Hydrogen Proton Magnetic Dipole Moment at Relaxation in The Blood as a Basis for Blood Pressure Monitoring http://jmrhs.info/index.php/jmrhs/article/view/75 <p><strong>The r</strong><strong>esearch has been carried out to create a non-invasive blood pressure monitoring system in the branchial artery of a sample based on a rotating of the magnetic spin dipole moments of proton in hydrogen atom. This is motivated by the fact that </strong><strong>change the population of a sudden and relaxation</strong><strong> of the magnetic spin dipole moment of a proton in the hydrogen atom shortly after passing through the gap between magnetic poles (the strength of 1,200 gauss) can produce an induced emf. The system utilizes two permanent magnets and the receiver coil, and the system is called a magnet coil system. In this research, the writer wants to produce a non-invasive monitor for blood pressure but based on pulses of blood pressure waves. This study aims to get the value of equality between electromotive force induction which is washed away with blood (in the branchial artery) to the value of blood pressure from a number of samples measured by a sphygmomanometer. In addition, the total reproducibility of the tool is also calculated. As for the methodology carried out is to place the sample arm between the two permanent magnetic poles with a magnitude of (7.3</strong><strong>0.</strong><strong>2)x10<sup>3</sup> gauss, and the electromotive induction is captured by receiver coil (involving 2,000 turns and 0.1 mm wire diameter). The receiver coil is connected with a digital storage oscilloscope. The result of equality between electromotive force induction&nbsp; (by rotation of the magnetic spin dipole moments of a proton in hydrogen atom at the time of relaxation) is obtained by the number of the digital sphygmomanometer from about 50 arms sample in the region of the induced electromotive force value of 0 to </strong><strong>80 mV</strong><strong> and sphygmomanometer of 0 to 220 mmHg. The induced emf value is 4 times greater than when using a permanent magnet whose magnetic field is only about 1,200 gausses. While the total reproducibility of the magnet coil system is (20</strong><strong>1).</strong></p> Bambang Murdaka Eka Jati, A.B.S. Utomo, G. Maruto, Y.R. Utomo ##submission.copyrightStatement## http://jmrhs.info/index.php/jmrhs/article/view/75 Tue, 23 Jul 2019 08:03:52 +0000