Omega-3 fats in herbs prevent heart complications

Abstract

The classification of the hyperlipidemia is transitioning from an older system based on phenotype to a newer system based on genetic or metabolic mechanism. Each system has gaps and overlaps, and the transition further complicates efforts to organize the causes and manifestations of dyslipidemia. As the pathophysiology of dyslipidemias is clarified, one system is likely to emerge in which the underlying mechanism explains the phenotypic pattern observed on lipoprotein analysis. Place and duration of study: Research study was conducted at Lahore General Hospital, Lahore from January 2018 to April 2018. Patients Inclusion/Exclusion criteria and Grouping: Forty hyperlipidemic patients were selected from Lahore General Hospital for the study. Age of patients ranged from 20 to 65 years. Both gender male and female patients were enrolled. They were advised to discontinue any hypolipidemic medications and foods. Patients suffering from any metabolic disease, renal impairment, liver disease, and already having any cardiac problems were excluded from the research study. Forty patients were divided in two groups, twenty individuals in each group.  Group-1 was advised to take 30 grams of walnuts (without shell) per day for the period of eight weeks. Group-II was considered as control group and was advised not to take any dry fruit including walnuts.  Methodology: Their baseline values of HDL-cholesterol were measured at day-0 and day-60, by  separating other lipoprotein fractions using  chemical precipitation with Mg²⁺, then coupling the products of a cholesterol oxidase reaction. Results: In twenty hyperlipidemic patients, two months therapy with 30 grams of walnuts per day increase in HDL-cholesterol was 6.3 mg/dl which was significant change when analyzed biostatistically, showing p-value <0.01.  Statistical analysis:  Mean values with SD and SEM were analysed statistically by using SPSS version 16.1.  P-value of <0.001 was considred  as significant and p-value of >0.05 was considered as non-significant change.  Conclusion: It was concluded from the study  that regular intake of specific amount of walnuts without shell can increase good cholesterol (HDL-cholesterol) in male and female patients of age range from 18 to 65 years. KEY WORDS: Lipids, herbs, CAD, prevention, cardiac, CCF