A Systematic Review of the Strontium Content of the Normal Human Prostate Gland

Abstract

A proposal has been made that prostatic strontium (Sr) content determinations may be useful in the prostate condition estimation and especially as an indicator of prostate carcinoma risk. Here we analyze data published concerning Sr prostatic levels in healthy subjects. All 2056 items in the literature of the years dating back to 1921 were identified in the following databases: PubMed, the Cochrane Library, Scopus, Web of Science, and ELSEVIER-EMBASE. The objective analysis was carried out on the data from the 26 studies, including 1453 subjects. It was found that the range of means of prostatic Sr content reported in the literature for “normal” gland widely varies from 0.16 mg/kg to <1.10 mg/kg with a median of means 0.398 mg/kg on a wet mass basis. The data encompassed a wide range of values and the sample was small, hence further studies should be performed.