Journal of Medical Research and Health Sciences

an Open Access Publication

Study on Lipid profile in hypothyroidism.

Dr Gopal Chandra Nath
Consultant Medicine, Department of Medicine, Guwahati Neurological Research Centre and Hospital,Guwahati,

Abstract

Background: Dyslipidemia is one of the common disorders seen in most of the hypothyroid patients. Objective: To study the lipid profile in patients with hypothyroidism.   Methods: The study was carried out in our hospital for a period of one year. The study included 100 hypothyroid  patients and 100 healthy  subjects .Their serum samples were assessed for TSH,T4 and T3 , total cholesterol , triglycerides, low density lipoprotein(LDL) cholesterol  and high density lipoprotein(HDL) cholesterol  by using standard biochemical methods after taking informed consent. Results: Out of 100 hypothyroid patients 45 (45%) were males and 55 (55%) were females. 75 patients presented with clinical hypothyroidism and 25 patients with subclinical hypothyroidism. Maximum number of patients were in age group of 30-45 years. 85.3% of clinical hypothyroid patients showed high serum cholesterol level, while 44% of subclinical hypothyroid patients showed high serum cholesterol level. 68% of subclinical hypothyroid patients showed high serum triglyceride level (>150mg/dl), while 85.3% of clinical hypothyroidism patients showed high triglyceride level.

Serum LDL level was high (>160 mg/dl) in 78.6% of patients with clinical hypothyroidism, while  68% of patients with subclinical hypothyroidism showed higher value. 40% of subclinical hypothyroid patients showed low(<40 mg/dl) serum HDL value while all patients with clinical hypothyroidism had low serum HDL level. Conclusion: The frequencies of the high cholesterol, high TG , high LDL with low HDL levels were higher in the hypothyroid group, thus indicating that hypothyroid patients were more prone for dyslipidemia, which  is a major risk factor for cardiovascular disorders.  

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How to Cite
Nath, D. G. C. (2019). Study on Lipid profile in hypothyroidism. Journal of Medical Research and Health Sciences, 2(5), 621-623. https://doi.org/10.15520/jmrhs.v2i5.63
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