Investigation of Kisspeptin Hormone and Vitamin D3 Levels in Infertile Men

Abstract

The aim of this study is to detection levels  of kisspeptin hormone and vitamin D₃ in oligozoospermia, asthenozoospermia and  unexplained  infertility in  men.                

    This study included the examination of 200 samples after a period of abstinence of 3-5 days, where samples were collected from patients with oligozoospermia            (50 samples), patients with asthenozoospermia (50 samples) and patients with unexplained infertility (50 samples) in comparison with control (50 samples) a control sample are between (21-45) years,    in the laboratory of the Fertility Center / Al-Sadr Medical City / Najaf Governorate from 20/1/2021 to 1/1/2022. 

 The results also showed a significant decrease (p<0.05) in the concentration of kisspeptin hormone for oligozoospermia, asthenozoospermia  and unexplained infertility  compared to the control group.

    Also the results showed a significant decrease (p<0.05) in the concentration of vitamin D₃ for oligozoospermia , asthenozoospermia, and unexplained infertility compared to the control group.

The results also showed a positive relationship between the kisspeptin hormone with vitamin D₃,  , sperm concentration  for  oligozoospermia, asthenozoospermia and unexplained infertile.

    The results also showed a positive relationship between vitamin D₃ with glutathione, sperm concentration, sperm motility and normal sperm Morphology for   oligozoospermia, asthenozoospermia and unexplained infertile.