Introduction: Congenital malformations are a global health problem around the world. MCs is one of the main causes of death and disability of newborns worldwide, but the majority of its risk factors are still poorly understood.

Objective: The aim of this study is to determine the main causes that are related to the incidence of congenital malformations (CMs) in the region of Agadir in Morocco.

Material and Methods: A prospective cases-control study at regional level was conducted in the pediatrics and neonatology department of Hassan II hospital in Agadir from April 2016 to April 2018. Data on child and maternal variables were recorded for 3701 newborns. The types of congenital malformations  have been classified according to the codes of the International Classification of Diseases. Univariate analyzes were performed to identify the variables associated with the etiology of the malformations. Multiple logistic regression was used to characterize the associations between the MC and the determining explanatory variables taken into account simultaneously.

Results: The results of these studies showed that there is a significant association between the incidence of the Congenital anomalies and the level of the consanguinity of the child, the prematurity of childbirth, the family history of CMs, the body mass index of the mother and the presence of major trauma during pregnancy.

Conclusion: our results have made it possible to highlight the existence of an association between a certain number of risk factors and the occurrence of congenital malformations. Additional studies are needed to confirm and clarify the role of these risk factors.

Introduction: Congenital malformations are a global health problem around the world. MCs is one of the main causes of death and disability of newborns worldwide, but the majority of its risk factors are still poorly understood.

Objective: The aim of this study is to determine the main causes that are related to the incidence of congenital malformations (CMs) in the region of Agadir in Morocco.

Material and Methods: A prospective cases-control study at regional level was conducted in the pediatrics and neonatology department of Hassan II hospital in Agadir from April 2016 to April 2018. Data on child and maternal variables were recorded for 3701 newborns. The types of congenital malformations  have been classified according to the codes of the International Classification of Diseases. Univariate analyzes were performed to identify the variables associated with the etiology of the malformations. Multiple logistic regression was used to characterize the associations between the MC and the determining explanatory variables taken into account simultaneously.

Results: The results of these studies showed that there is a significant association between the incidence of the Congenital anomalies and the level of the consanguinity of the child, the prematurity of childbirth, the family history of CMs, the body mass index of the mother and the presence of major trauma during pregnancy.

Conclusion: our results have made it possible to highlight the existence of an association between a certain number of risk factors and the occurrence of congenital malformations. Additional studies are needed to confirm and clarify the role of these risk factors.

Introduction: Congenital malformations are a global health problem around the world. MCs is one of the main causes of death and disability of newborns worldwide, but the majority of its risk factors are still poorly understood.

Objective: The aim of this study is to determine the main causes that are related to the incidence of congenital malformations (CMs) in the region of Agadir in Morocco.

Material and Methods: A prospective cases-control study at regional level was conducted in the pediatrics and neonatology department of Hassan II hospital in Agadir from April 2016 to April 2018. Data on child and maternal variables were recorded for 3701 newborns. The types of congenital malformations  have been classified according to the codes of the International Classification of Diseases. Univariate analyzes were performed to identify the variables associated with the etiology of the malformations. Multiple logistic regression was used to characterize the associations between the MC and the determining explanatory variables taken into account simultaneously.

Results: The results of these studies showed that there is a significant association between the incidence of the Congenital anomalies and the level of the consanguinity of the child, the prematurity of childbirth, the family history of CMs, the body mass index of the mother and the presence of major trauma during pregnancy.

Conclusion: our results have made it possible to highlight the existence of an association between a certain number of risk factors and the occurrence of congenital malformations. Additional studies are needed to confirm and clarify the role of these risk factors.

Introduction: Congenital malformations are a global health problem around the world. MCs is one of the main causes of death and disability of newborns worldwide, but the majority of its risk factors are still poorly understood.

Objective: The aim of this study is to determine the main causes that are related to the incidence of congenital malformations (CMs) in the region of Agadir in Morocco.

Material and Methods: A prospective cases-control study at regional level was conducted in the pediatrics and neonatology department of Hassan II hospital in Agadir from April 2016 to April 2018. Data on child and maternal variables were recorded for 3701 newborns. The types of congenital malformations  have been classified according to the codes of the International Classification of Diseases. Univariate analyzes were performed to identify the variables associated with the etiology of the malformations. Multiple logistic regression was used to characterize the associations between the MC and the determining explanatory variables taken into account simultaneously.

Results: The results of these studies showed that there is a significant association between the incidence of the Congenital anomalies and the level of the consanguinity of the child, the prematurity of childbirth, the family history of CMs, the body mass index of the mother and the presence of major trauma during pregnancy.

Conclusion: our results have made it possible to highlight the existence of an association between a certain number of risk factors and the occurrence of congenital malformations. Additional studies are needed to confirm and clarify the role of these risk factors.

Statistics from Hungary over the last seven years clearly show that diseases of the circulatory device lead the statistics on the causes of death. The Hungarian trend is the same as the global trend, with circulatory system disease being the most common cause of death in every country. The modeling of the blood volume, if we administer a certain substance amount, then its passing speed will depend on its concentration, hence the volume at which it spreads in the deposit. Consider the contraction and relaxation of the atrium/ventricle of the human heart; use the function of the rhythmic change for this. We apply the calorimetric principles for the measurement of the gastric blood flow. In the physio­pathology research of the circulation in arteriopathic people, when there are necessary arguments refering to the efficiency of new medicines or for the purpose of reestablishing the work capacity, the clinic diagnostic must be completed with laboratory samples: regional debt, peripheral arterial resistance, circulation time. Its measuring can be made with a normal double walls calorimeter and we measure the water temperature variations. Knowing the values of the previous formulas and the mass of blood circulated in that segment, we find out the segment’s flow. The human organism is a system because it is made up of a finite number of interacting p₁, p₂,… p_n elements, characterized by the quantitative degree of q₁, q₂,… q_n. The circulatory apparatus is a subsystem of the human body. In our opinion, the circulatory device should have a control associated with its own structure, which is likely to consist of neurons with hyperordonated spatial structure, called the “hypothetical secondary brain”, which performs certain control functions. This “hypothetical secondary brain” of the circulatory apparatus, in humans, functions continuously throughout their life.

Statistics from Hungary over the last seven years clearly show that diseases of the circulatory device lead the statistics on the causes of death. The Hungarian trend is the same as the global trend, with circulatory system disease being the most common cause of death in every country. The modeling of the blood volume, if we administer a certain substance amount, then its passing speed will depend on its concentration, hence the volume at which it spreads in the deposit. Consider the contraction and relaxation of the atrium/ventricle of the human heart; use the function of the rhythmic change for this. We apply the calorimetric principles for the measurement of the gastric blood flow. In the physio­pathology research of the circulation in arteriopathic people, when there are necessary arguments refering to the efficiency of new medicines or for the purpose of reestablishing the work capacity, the clinic diagnostic must be completed with laboratory samples: regional debt, peripheral arterial resistance, circulation time. Its measuring can be made with a normal double walls calorimeter and we measure the water temperature variations. Knowing the values of the previous formulas and the mass of blood circulated in that segment, we find out the segment’s flow. The human organism is a system because it is made up of a finite number of interacting p₁, p₂,… p_n elements, characterized by the quantitative degree of q₁, q₂,… q_n. The circulatory apparatus is a subsystem of the human body. In our opinion, the circulatory device should have a control associated with its own structure, which is likely to consist of neurons with hyperordonated spatial structure, called the “hypothetical secondary brain”, which performs certain control functions. This “hypothetical secondary brain” of the circulatory apparatus, in humans, functions continuously throughout their life.

Statistics from Hungary over the last seven years clearly show that diseases of the circulatory device lead the statistics on the causes of death. The Hungarian trend is the same as the global trend, with circulatory system disease being the most common cause of death in every country. The modeling of the blood volume, if we administer a certain substance amount, then its passing speed will depend on its concentration, hence the volume at which it spreads in the deposit. Consider the contraction and relaxation of the atrium/ventricle of the human heart; use the function of the rhythmic change for this. We apply the calorimetric principles for the measurement of the gastric blood flow. In the physio­pathology research of the circulation in arteriopathic people, when there are necessary arguments refering to the efficiency of new medicines or for the purpose of reestablishing the work capacity, the clinic diagnostic must be completed with laboratory samples: regional debt, peripheral arterial resistance, circulation time. Its measuring can be made with a normal double walls calorimeter and we measure the water temperature variations. Knowing the values of the previous formulas and the mass of blood circulated in that segment, we find out the segment’s flow. The human organism is a system because it is made up of a finite number of interacting p₁, p₂,… p_n elements, characterized by the quantitative degree of q₁, q₂,… q_n. The circulatory apparatus is a subsystem of the human body. In our opinion, the circulatory device should have a control associated with its own structure, which is likely to consist of neurons with hyperordonated spatial structure, called the “hypothetical secondary brain”, which performs certain control functions. This “hypothetical secondary brain” of the circulatory apparatus, in humans, functions continuously throughout their life.

Statistics from Hungary over the last seven years clearly show that diseases of the circulatory device lead the statistics on the causes of death. The Hungarian trend is the same as the global trend, with circulatory system disease being the most common cause of death in every country. The modeling of the blood volume, if we administer a certain substance amount, then its passing speed will depend on its concentration, hence the volume at which it spreads in the deposit. Consider the contraction and relaxation of the atrium/ventricle of the human heart; use the function of the rhythmic change for this. We apply the calorimetric principles for the measurement of the gastric blood flow. In the physio­pathology research of the circulation in arteriopathic people, when there are necessary arguments refering to the efficiency of new medicines or for the purpose of reestablishing the work capacity, the clinic diagnostic must be completed with laboratory samples: regional debt, peripheral arterial resistance, circulation time. Its measuring can be made with a normal double walls calorimeter and we measure the water temperature variations. Knowing the values of the previous formulas and the mass of blood circulated in that segment, we find out the segment’s flow. The human organism is a system because it is made up of a finite number of interacting p₁, p₂,… p_n elements, characterized by the quantitative degree of q₁, q₂,… q_n. The circulatory apparatus is a subsystem of the human body. In our opinion, the circulatory device should have a control associated with its own structure, which is likely to consist of neurons with hyperordonated spatial structure, called the “hypothetical secondary brain”, which performs certain control functions. This “hypothetical secondary brain” of the circulatory apparatus, in humans, functions continuously throughout their life.